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Parker Robinson
Parker Robinson

Genetica Molecular Humana: A Comprehensive Textbook by Strachan and Read


Genetica Molecular Humana Strachan Pdf Download




If you are looking for a comprehensive and up-to-date textbook on molecular genetics, you might want to check out Genetica Molecular Humana by Tom Strachan and Andrew Read. This book, which is also known as Human Molecular Genetics in English, is one of the most popular and widely used books in the field. It covers all the essential topics in molecular genetics, from DNA structure and gene expression to genetic variation and evolution. It also includes practical examples and case studies that illustrate how molecular genetics is applied in medicine, biotechnology, and other areas. In this article, we will give you an overview of the book and its contents, as well as show you how to download it in PDF format.




Genetica Molecular Humana Strachan Pdf Download



What is molecular genetics and why is it important?




Molecular genetics is the branch of biology that studies the structure, function, and regulation of genes and genomes at the molecular level. It aims to understand how genes encode information for proteins and other molecules that perform various roles in cells and organisms. It also investigates how genes interact with each other and with environmental factors to influence traits such as appearance, behavior, development, health, and disease.


Molecular genetics is important because it provides insights into the fundamental mechanisms of life. It helps us to discover how life evolved from simple molecules to complex organisms. It also enables us to manipulate genes and genomes for various purposes, such as improving crops, developing drugs, diagnosing diseases, or creating new forms of life.


What are the main topics covered in the book?




The book consists of 10 chapters that cover the following topics:


Chapter 1: DNA structure and gene expression




This chapter introduces the basic concepts of molecular genetics, such as DNA structure, replication, transcription, translation, and regulation. It explains how DNA is organized and regulated in prokaryotic and eukaryotic cells. It also describes how genes are identified and characterized by molecular techniques such as PCR, cloning, hybridization, sequencing, microarrays, RNA interference, and CRISPR-Cas9.


Chapter 2: Chromosomes and cell division




This chapter discusses the structure and function of chromosomes and how they are inherited and maintained during cell division. It covers topics such as chromatin, histones, nucleosomes, chromosomal abnormalities, karyotypes, mitosis, meiosis, and gametogenesis. It also explains how chromosome number and structure can vary among different species and individuals.


Chapter 3: Genomes and mapping




This chapter explores the concept of genomes and how they are sequenced and analyzed. It covers topics such as genome size, complexity, organization, annotation, comparison, and evolution. It also describes how genetic maps are constructed and used to locate genes and markers on chromosomes.


Chapter 4: Mutations and DNA repair




This chapter examines the causes and consequences of mutations and how they are corrected or tolerated by cells. It covers topics such as mutation types, rates, effects, detection, classification, and nomenclature. It also explains how DNA repair mechanisms prevent or fix DNA damage caused by various agents such as chemicals, radiation, or errors during replication.


Chapter 5: Recombination and transposition




This chapter investigates how DNA segments are rearranged or moved within or between genomes. It covers topics such as homologous recombination, non-homologous end joining, site-specific recombination, transposition, retrotransposition, gene conversion, gene duplication, gene fusion, gene fission, and horizontal gene transfer. It also illustrates how recombination and transposition can generate genetic diversity and affect genome evolution.


Chapter 6: Genetic variation and evolution




This chapter explores how genetic diversity is generated and shaped by natural selection and other evolutionary forces. It covers topics such as polymorphism, allele frequency, genotype frequency, Hardy-Weinberg equilibrium, genetic drift, gene flow, mutation-selection balance, inbreeding, outbreeding, adaptation, speciation, phylogeny, molecular clock, molecular evolution, and molecular phylogenetics. It also shows how molecular genetics can be used to study the origin and evolution of life on Earth.


Chapter 7: Genetic analysis of populations




Chapter 8: Human genetic diversity and disease




This chapter explores how human genetic variation influences health and disease susceptibility. It covers topics such as human genetic history, human genetic variation, human genome project, human haplotype map, human reference genome, personal genomics, pharmacogenomics, monogenic diseases, polygenic diseases, complex diseases, multifactorial diseases, gene-environment interaction, epigenetics, and gene therapy.


Chapter 9: Genetic manipulation of organisms




This chapter discusses how genetic engineering techniques are used to modify or create organisms with desired traits. It covers topics such as recombinant DNA technology, restriction enzymes, vectors, plasmids, transformation, transfection, transduction, electroporation, microinjection, biolistics, gene targeting, gene editing, knockout mice, transgenic animals, transgenic plants, genetically modified organisms (GMOs), biosafety, bioethics, and biotechnology.


Chapter 10: Genomics and systems biology




This chapter describes how genomics and bioinformatics tools are used to study complex biological systems. It covers topics such as functional genomics, transcriptomics, proteomics, metabolomics, interactomics, network biology, systems biology, synthetic biology, and systems medicine. It also explains how these approaches can help to understand the molecular basis of diseases and to develop new diagnostic and therapeutic strategies.


What are the benefits of downloading the book in PDF format?




Downloading the book in PDF format has several advantages over other formats such as hardcopy, e-book, or online access. Some of these advantages are:



  • PDF files are compatible with most devices and platforms. You can read them on your computer, tablet, smartphone, or e-reader without any problem.



  • PDF files are easy to download and store. You can save them on your device or on a cloud service and access them anytime and anywhere.



  • PDF files are easy to print. You can print them on any printer without losing quality or formatting.



  • PDF files are easy to share. You can send them by email or other means to your friends or colleagues who might be interested in the book.



  • PDF files are easy to annotate. You can highlight, underline, comment, or bookmark any part of the book that you find important or interesting.



  • PDF files are secure. You can protect them with a password or a digital signature to prevent unauthorized access or modification.



How to download the book in PDF format?




If you want to download the book in PDF format, you have several options to choose from. Here are some of them:



  • You can buy the book from the official website of the publisher Garland Science. You will get a PDF file that you can download and use for personal use only.



  • You can buy the book from online retailers such as Amazon or Barnes & Noble. You will get an e-book that you can read on your device or app. Some e-books may allow you to convert them to PDF files using third-party software.



  • You can borrow the book from a library that has a digital collection. You will need a library card and an app such as OverDrive or Hoopla. You will be able to download the book for a limited period of time and read it on your device or app.



  • You can find the book on a file-sharing website such as Library Genesis or Z-Library. You will be able to download the book for free and read it on your device or app. However, this option may be illegal or unethical depending on your location and the copyright status of the book.



Whichever option you choose, make sure that you have a reliable internet connection and enough storage space on your device. Also, make sure that you respect the rights of the authors and the publishers and use the book for educational purposes only.


Conclusion




In conclusion, Genetica Molecular Humana by Tom Strachan and Andrew Read is a great book for anyone who wants to learn more about molecular genetics. It covers all the essential topics in the field, from DNA structure and gene expression to genetic variation and evolution. It also includes practical examples and case studies that illustrate how molecular genetics is applied in medicine, biotechnology, and other areas. You can download the book in PDF format from various sources and enjoy its benefits such as compatibility, convenience, printability, shareability, annotability, and security. We hope that this article has helped you to get an overview of the book and its contents, as well as how to download it in PDF format.


FAQs




Here are some frequently asked questions about the book and its PDF download:



  • Who are the authors of the book?



The authors of the book are Tom Strachan and Andrew Read. Tom Strachan is a professor emeritus of human molecular genetics at Newcastle University in the UK. He has authored or co-authored several books and articles on molecular genetics and genomics. Andrew Read is a professor of human genetics at the University of Manchester in the UK. He has authored or co-authored several books and articles on human genetics and genetic diseases.


  • What is the edition and publication date of the book?



The book is currently in its fifth edition, which was published in 2019 by Garland Science. The first edition was published in 1996 by Wiley-Liss.


  • What is the ISBN of the book?



The ISBN of the book is 978-0-8153-4149-9 for the hardcover version and 978-1-138-23860-5 for the e-book version.


  • How many pages does the book have?



The book has 784 pages, including 10 chapters, a glossary, an index, and references.


  • How much does the book cost?



The book costs $140 for the hardcover version and $70 for the e-book version on the publisher's website. The price may vary depending on the retailer or the source.


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